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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LCP1 All Species: 27.27
Human Site: S421 Identified Species: 54.55
UniProt: P13796 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P13796 NP_002289.2 627 70289 S421 N H L Y S D L S D A L V I F Q
Chimpanzee Pan troglodytes XP_001157345 627 70271 S421 N H L Y S D L S D A L V I F Q
Rhesus Macaque Macaca mulatta XP_001098408 627 70284 S421 N H L Y S D L S D A L V I F Q
Dog Lupus familis XP_848404 601 67450 N410 W M N S L G V N P R V N H L Y
Cat Felis silvestris
Mouse Mus musculus Q61233 627 70131 S421 N H L Y S D L S D A L V I F Q
Rat Rattus norvegicus Q63598 630 70661 Q424 N H L Y V D L Q D A L V I L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514284 674 75344 S468 N H L Y S D L S D A L V I F Q
Chicken Gallus gallus P19179 630 70921 S423 N H L Y S D L S D A L I I F Q
Frog Xenopus laevis NP_001080219 616 69050 S411 N H L Y S D L S D A L I I F Q
Zebra Danio Brachydanio rerio Q6P698 624 69882 A419 N H L Y V D L A D A L V I F Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q7G188 687 76910 R419 N N V F E D V R N G W I L L E
Baker's Yeast Sacchar. cerevisiae P32599 642 71754 K438 I S L F D D L K D G L I L L Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 100 99.6 92.5 N.A. 96.9 78.8 N.A. 86 71.1 85.8 82.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 100 100 94.4 N.A. 99.1 88.7 N.A. 90.2 83.8 93.1 91.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 100 80 N.A. 100 93.3 93.3 86.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 20 N.A. 100 80 N.A. 100 100 100 93.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 33.9 37.8 N.A.
Protein Similarity: N.A. N.A. N.A. 55.3 57.4 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 75 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 9 92 0 0 84 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 9 % E
% Phe: 0 0 0 17 0 0 0 0 0 0 0 0 0 67 0 % F
% Gly: 0 0 0 0 0 9 0 0 0 17 0 0 0 0 0 % G
% His: 0 75 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 34 75 0 0 % I
% Lys: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 84 0 9 0 84 0 0 0 84 0 17 34 0 % L
% Met: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 84 9 9 0 0 0 0 9 9 0 0 9 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 84 % Q
% Arg: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % R
% Ser: 0 9 0 9 59 0 0 59 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 9 0 17 0 17 0 0 0 9 59 0 0 0 % V
% Trp: 9 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % W
% Tyr: 0 0 0 75 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _